Bioc 201 Midterm 1 Review Cheat Sheet (DRAFT) by VanessaG

Protein folding

not very efficient = about 30% of all newly synthe­sized polype­ptides are misfolded and tagged

Primary structure
linear polype­ptide chain -- amino acids linked together

initial folding of linear polype­ptide is driven by hydrogen bond formation of polype­ptide backbone to form alpha-­helices and beta-s­heets - to form the secondary structure

tertiary driven hydrop­hobic collapse

Enzymes

often change shape when they bind their substr­ate(s).

NOT always protien